When ambitious real estate developer Dan Sanders (Brendan Fraser) relocates his family to rural Oregon to supervise the construction of a massive new subdivision, one resourceful raccoon rallies his woodland friends to fight back and shut down the project. As the battle between man and beast heats up, the hapless real estate developer realizes there are some natural environments that are better left untouched.

As a toxin begins to turn the residents of Ogden Marsh, Iowa into violent psychopaths, sheriff David Dutton (Olyphant) tries to make sense of the situation while he, his wife (Mitchell), and two other unaffected townspeople band together in a fight for survival.

A young boy’s discovery of a colorful, wish-granting rock causes chaos in the suburban town of Black Falls when jealous kids and scheming adults alike set out to get their hands on it.